Beta-globin gene cluster haplotypes in sickle cell patients from southwest Iran.

@article{Rahimi2003BetaglobinGC,
  title={Beta-globin gene cluster haplotypes in sickle cell patients from southwest Iran.},
  author={Zohreh Rahimi and Masoumeh Karimi and Mansour Haghshenass and Ahmad Merat},
  journal={American journal of hematology},
  year={2003},
  volume={74 3},
  pages={
          156-60
        }
}
Sickle cell anemia in Iran is accompanied by a high level of HbF and mild clinical presentation. Here we report haplotypes of the beta gene cluster found in 81 randomly selected sickle cell patients, including 47 sickle cell anemia (SS), 17 sickle cell trait (AS), and 17 sickle/thalassemia (S/thal) from southwest Iran. We found all five common typical haplotypes as well as five atypical haplotypes in our patients. Except for four patients with homozygous Benin haplotype, none of the other… CONTINUE READING
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