Beta-endorphin activity and hypercapnic ventilatory responsiveness after marathon running.

@article{Mahler1989BetaendorphinAA,
  title={Beta-endorphin activity and hypercapnic ventilatory responsiveness after marathon running.},
  author={Donald A. Mahler and Lee N. Cunningham and Gary S. Skrinar and William J. Kraemer and Gene L. Colice},
  journal={Journal of applied physiology},
  year={1989},
  volume={66 5},
  pages={2431-6}
}
To investigate the hypothesis that endurance exercise may lead to a decrease in ventilatory chemosensitivity as possibly mediated by an increase in endogenous beta-endorphins, we measured hypercapnic ventilatory responsiveness (HCVR) and circulating beta-endorphin immunoreactivity in six runners before and after a marathon (42.2 km) race and after administration of 10 mg iv naloxone. Similar testing was performed at identical time periods on the day before the marathon as control data. On each… CONTINUE READING