Beta-defensin 126 on the cell surface protects sperm from immunorecognition and binding of anti-sperm antibodies.

@article{Yudin2005Betadefensin1O,
  title={Beta-defensin 126 on the cell surface protects sperm from immunorecognition and binding of anti-sperm antibodies.},
  author={Ashley I. Yudin and Suzanne E Generao and Theodore L. Tollner and Catherine A Treece and James W. Overstreet and Gary N Cherr},
  journal={Biology of reproduction},
  year={2005},
  volume={73 6},
  pages={1243-52}
}
Beta-defensin 126 (DEFB126), formerly known as epididymal secretory protein 13.2 (ESP13.2), coats the entire primate sperm surface until completion of capacitation, and it is a candidate for providing immune protection in the female reproductive tract. To further examine the potential role of DEFB126 as a means of protection from immune recognition, cynomolgus macaque sperm were exposed to a number of treatments that are known to alter sperm surface coats, including capacitation. We used a… CONTINUE READING