Beta-cyclodextrin as a suitable solubilizing agent for in situ absorption study of poorly water-soluble drugs.

Abstract

To evaluate the intestinal permeability of poorly water-soluble compounds, it is of importance to completely dissolve them in a medium and to avoid precipitation during experiments. This study was undertaken to find an agent possessing a high-solubilizing capacity and exhibiting minimal modulating impact on membrane integrity and absorption systems such as… (More)

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