Beta clamp directs localization of mismatch repair in Bacillus subtilis.

Abstract

MutS homologs function in several cellular pathways including mismatch repair (MMR), the process by which mismatches introduced during DNA replication are corrected. We demonstrate that the C terminus of Bacillus subtilis MutS is necessary for an interaction with beta clamp. This interaction is required for MutS-GFP focus formation in response to mismatches… (More)
DOI: 10.1016/j.molcel.2007.10.036

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