Beta-cell mass and proliferation following late fetal and early postnatal malnutrition in the rat

@article{Garofano1998BetacellMA,
  title={Beta-cell mass and proliferation following late fetal and early postnatal malnutrition in the rat},
  author={Anna Garofano and Paul C Czernichow and B. Breant},
  journal={Diabetologia},
  year={1998},
  volume={41},
  pages={1114-1120}
}
We have recently shown that maternal food restriction during late pregnancy in rats decreased beta-cell mass in the offspring at birth, without altering beta-cell proliferation. The aim of the present work was to determine: 1) whether sustained maternal undernutrition until weaning (R group) more dramatically alters beta-cell mass in the offspring and if normal food supply from weaning until adulthood could reverse the deleterious effects and; 2) if altered beta-cell proliferation was… CONTINUE READING

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