Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study

Abstract

Both insulin resistance and beta-cell dysfunction play a role in the transition from normal glucose tolerance (NGT) to Type 2 diabetes (T2DM) through impaired glucose tolerance (IGT). The aim of the study was to define the level of glycaemia at which beta-cell dysfunction becomes evident in the context of existing insulin resistance. Insulin response (OGTT… (More)
DOI: 10.1007/s00125-003-1263-9

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@article{Gastaldelli2003BetacellDA, title={Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study}, author={Amalia Gastaldelli and Ele Ferrannini and Yasusuke Miyazaki and Mitsumasa Matsuda and Ralph DeFronzo}, journal={Diabetologia}, year={2003}, volume={47}, pages={31-39} }