Beta-catenin patterns the cell cycle during maternal-to-zygotic transition in urochordate embryos.

@article{Dumollard2013BetacateninPT,
  title={Beta-catenin patterns the cell cycle during maternal-to-zygotic transition in urochordate embryos.},
  author={R{\'e}mi Dumollard and C{\'e}line H{\'e}bras and Lydia Besnardeau and Alex McDougall},
  journal={Developmental biology},
  year={2013},
  volume={384 2},
  pages={331-42}
}
During the transition from maternal to zygotic control of development, cell cycle length varies in different lineages, and this is important for their fates and functions. The maternal to zygotic transition (MZT) in metazoan embryos involves a profound remodeling of the cell cycle: S phase length increases then G2 is introduced. Although β-catenin is the master regulator of endomesoderm patterning at MZT in all metazoans, the influence of maternal β-catenin on the cell cycle at MZT remains… CONTINUE READING