Beta-catenin is critical for dendritic morphogenesis.

  title={Beta-catenin is critical for dendritic morphogenesis.},
  author={Xiang Yu and Robert C Malenka},
  journal={Nature neuroscience},
  volume={6 11},
Regulated growth and arborization of dendritic processes are critical to the formation of functional neuronal networks. Here we identify beta-catenin as a critical mediator of dendritic morphogenesis. We found that increasing the intracellular levels of beta-catenin and other members of the cadherin/catenin complex, namely N-cadherin and alphaN-catenin, enhances dendritic arborization in rat hippocampal neurons, an effect that does not require Wnt/beta-catenin-dependent transcription… CONTINUE READING
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