Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial.

@article{Wilhelmsen1987BetablockersVD,
  title={Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial.},
  author={Linn Wilhelmsen and G{\"o}ran GB Berglund and D. B. Elmfeldt and T E Fitzsimons and Heinrich Holzgreve and James Hosie and P E H{\"o}rnkvist and Kjell M Pennert and Jaakko Tuomilehto and Hans Wedel},
  journal={Journal of hypertension},
  year={1987},
  volume={5 5},
  pages={561-72}
}
Men aged 40-64 years with mild to moderate hypertension [diastolic blood pressure (DBP) 100-130 mmHg] were randomized to treatment with a diuretic (n = 3272) or a beta-blocker (n = 3297), with additional drugs if necessary, to determine whether a beta-blocker based treatment differs from thiazide diuretic based treatment with regard to the prevention of coronary heart disease (CHD) events and death. Patients with previous CHD, stroke or other serious diseases, or with contraindications to… CONTINUE READING