Beta-barrel scaffold of fluorescent proteins: folding, stability and role in chromophore formation.

@article{Stepanenko2013BetabarrelSO,
  title={Beta-barrel scaffold of fluorescent proteins: folding, stability and role in chromophore formation.},
  author={Olesya V Stepanenko and Olga V. Stepanenko and Irina M. Kuznetsova and Vladislav V. Verkhusha and Konstantin K Turoverov},
  journal={International review of cell and molecular biology},
  year={2013},
  volume={302},
  pages={
          221-78
        }
}
  • Olesya V Stepanenko, Olga V. Stepanenko, +2 authors Konstantin K Turoverov
  • Published in
    International review of cell…
    2013
  • Biology, Chemistry, Medicine
  • This review focuses on the current view of the interaction between the β-barrel scaffold of fluorescent proteins and their unique chromophore located in the internal helix. The chromophore originates from the polypeptide chain and its properties are influenced by the surrounding protein matrix of the β-barrel. On the other hand, it appears that a chromophore tightens the β-barrel scaffold and plays a crucial role in its stability. Furthermore, the presence of a mature chromophore causes… CONTINUE READING

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