Beta-adrenergic vasodilator mechanism in the finger.

  title={Beta-adrenergic vasodilator mechanism in the finger.},
  author={Richard Alan Cohen and Jay D. Coffman},
  journal={Circulation research},
  volume={49 5},
The digital vasospastic phenomena, which are induced by beta-adrenergic-blocking agents, suggest a beta-adrenergic finger vasodilator mechanism. We measured fingertip total blood flow with venous occlusion plethysmography and studied nutritional blood flow with Na131I clearance. During fingertip vasoconstriction caused by branchial artery infusion of norepinephrine or angiotensin, intra-arterial isoproterenol caused a sustained increase in fingertip total blood flow. Furthermore, propranolol… CONTINUE READING