Beta adrenergic regulation of rat liver glycogenolysis during aging

@article{Katz1993BetaAR,
  title={Beta adrenergic regulation of rat liver glycogenolysis during aging},
  author={Michael S. Katz and Elizabeth M. Dax and Robert I. Gregerman},
  journal={Experimental Gerontology},
  year={1993},
  volume={28},
  pages={329-340}
}
Studies from a number of laboratories demonstrate a biphasic change in beta adrenergic regulation of hepatic glycogenolysis over the life span of the male rat. The beta adrenergic response is prominent in immature animals, declines rapidly during subsequent development to a minimum by the time of young adulthood, and then reemerges during postmaturational development. Age changes in beta adrenergic-responsive adenylate cyclase activity follow a "U"-shaped curve similar to that described by… CONTINUE READING
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