Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.

@article{Dax1987BetaadrenergicRG,
  title={Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.},
  author={Elizabeth M. Dax and John S. Partilla and Marco A Pineyro and Robert I. Gregerman},
  journal={Endocrinology},
  year={1987},
  volume={120 4},
  pages={
          1534-41
        }
}
The beta-adrenergic and glucagon receptor-binding capacities in rat livers from 6-27 months of age were measured to investigate the mechanism of a previously observed rise in beta-adrenergic stimulated adenylate cyclase with increasing age. There was no concomitant increase in glucagon-stimulated adenylate cyclase. In the present study neither glucagon-binding capacity nor glucagon-stimulated adenylate cyclase changed with age. In contrast, the beta-adrenergic receptor capacity, measured in the… CONTINUE READING