Beta S haplotypes in various world populations.

  title={Beta S haplotypes in various world populations.},
  author={C Naci Oner and Aleksandar Dimovski and Nancy F. Olivieri and Gino Schilir{\`o} and J F Codrington and Sladdehine Fattoum and Adekunle D Adekile and Reyhan Oner and Gunes T. Y{\"u}regir and Ciğdem Altay},
  journal={Human genetics},
  volume={89 1},
We have determined the beta S haplotypes in 709 patients with sickle cell anemia, 30 with SC disease, 91 with S-beta-thalassemia, and in 322 Hb S heterozygotes from different countries. The methodology concerned the detection of mutations in the promoter sequences of the G gamma- and A gamma-globin genes through dot blot analysis of amplified DNA with 32P-labeled probes, and an analysis of isolated Hb F by reversed phase high performance liquid chromatography to detect the presence of the A… CONTINUE READING
Highly Cited
This paper has 70 citations. REVIEW CITATIONS


Publications citing this paper.

71 Citations

Citations per Year
Semantic Scholar estimates that this publication has 71 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…