Beta-2-microglobulin for differentiation between ciclosporin A nephrotoxicity and graft rejection in renal transplant recipients.

@article{Prischl1989Beta2microglobulinFD,
  title={Beta-2-microglobulin for differentiation between ciclosporin A nephrotoxicity and graft rejection in renal transplant recipients.},
  author={Friedrich C. Prischl and Franz Gremmel and Michael Schwabe and John Schindler and Peter Balcke and Herbert Kopsa and Gg Pinter and Josef Schwarzmeier and Jan Zazgornik},
  journal={Nephron},
  year={1989},
  volume={51 3},
  pages={
          330-7
        }
}
The clinical relevance of daily measurement of beta 2-microglobulin in serum and urine was evaluated in 49 patients undergoing renal transplantation. The changes in beta 2-microglobulin levels were compared to standard parameters for assessment of renal function. One hundred episodes of acute deterioration of renal function, clinically diagnosed as rejection, were analyzed retrospectively: (1) In 18 episodes renal malfunction did not respond to methylprednisone but improved immediately upon… CONTINUE READING