Beta-2-microglobulin expression correlates with high-grade prostate cancer and specific defects in androgen signaling.


BACKGROUND Previously, we identified Beta-2-microglobulin (beta2M) as an androgen-regulated secreted protein elevated in the serum of prostate cancer patients. In this study, we explore an interaction between beta2M expression, prostate cancer tissue, and the androgen signaling axis. METHODS beta2M expression in relation to clinical and pathologic… (More)
DOI: 10.1002/pros.21155