Beta 1,4 N-acetylgalactosaminyltransferase (GM2/GD2/GA2 synthase) forms homodimers in the endoplasmic reticulum: a strategy to test for dimerization of Golgi membrane proteins.

@article{Zhu1997Beta1N,
  title={Beta 1,4 N-acetylgalactosaminyltransferase (GM2/GD2/GA2 synthase) forms homodimers in the endoplasmic reticulum: a strategy to test for dimerization of Golgi membrane proteins.},
  author={Guang Feng Zhu and Ewa Jaskiewicz and Roberto Bassi and Douglas S. Darling and William W. Young},
  journal={Glycobiology},
  year={1997},
  volume={7 7},
  pages={987-96}
}
Many Golgi membrane-bound glycosyltransferases exist as intermolecular disulfide bonded species, some of which have been demonstrated to be homodimers. Evidence for homodimer formation has come primarily from radiation inactivation experiments. We utilized an alternative strategy to test for homodimer formation of the cloned beta 1,4 N… CONTINUE READING