Beta-1,2-linked oligomannosides inhibit Candida albicans binding to murine macrophage.

@article{Fradin1996Beta12linkedOI,
  title={Beta-1,2-linked oligomannosides inhibit Candida albicans binding to murine macrophage.},
  author={C. Fradin and Thierry Jouault and A. Mallet and Jean Maurice Mallet and Daniel Camus and Pierre Sina{\"y} and Daniel Poulain},
  journal={Journal of leukocyte biology},
  year={1996},
  volume={60 1},
  pages={81-7}
}
Interaction of Candida albicans with cells of the macrophage lineage was examined by using heat-killed (HK) and live yeast cells. Laminarin, an analogue of the cell wall beta-glucans, strongly inhibited HK yeasts adherence to J774 cell line but had no effect on live yeast binding. Phosphopeptidomannan (PPM) from Saccharomyces cerevisiae had a limited effect on the binding of both HK and live yeasts but significant inhibition was achieved by the use of C. albicans PPM. The role of beta-1,2… CONTINUE READING