Best anesthetics for assessing left ventricular systolic function by echocardiography in mice.

@article{Pachon2015BestAF,
  title={Best anesthetics for assessing left ventricular systolic function by echocardiography in mice.},
  author={Ronald E. Pachon and Bruce A Scharf and Dorothy E. Vatner and Stephen F. Vatner},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2015},
  volume={308 12},
  pages={
          H1525-9
        }
}
Our review of the literature of the major cardiovascular journals for the past three years showed that for all studies using anesthesia for mouse echocardiography, the predominant anesthetic was isoflurane, which was used in 76% of the studies. The goal of this investigation was to determine if isoflurane is indeed the best anesthetic. Accordingly, we compared isoflurane with 2,2,2-tribromoethanol (Avertin), ketamine-xylazine, and ketamine on different days in the same 14 mice, also studied in… CONTINUE READING
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