Bergmann Glia Function in Granule Cell Migration During Cerebellum Development

  title={Bergmann Glia Function in Granule Cell Migration During Cerebellum Development},
  author={Haiwei Xu and Yang Yang and Xiaotong Tang and Meina Zhao and Fucheng Liang and Pei Yu Xu and Baoke Hou and Yan Xing and Xiaohang Bao and Xiaotang Fan},
  journal={Molecular Neurobiology},
Granule cell migration influences the laminar structure of the cerebellum and thereby affects cerebellum function. Bergmann glia are derived from radial glial cells and aid in granule cell radial migration by providing a scaffold for migration and by mediating interactions between Bergmann glia and granule cells. In this review, we summarize Bergmann glia characteristics and the mechanisms underlying the effect of Bergmann glia on the radial migration of granule neurons in the cerebellum… CONTINUE READING

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47:833–844 843 development requires expression of beta 1-integrin in Bergmann glia, but not in granule neurons

  • A Frick, D Grammel, +10 authors U Schuller
  • Proper cerebellar Mol Neurobiol
  • 2012
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