Berberine up-regulates hepatic low-density lipoprotein receptor through Ras-independent but AMP-activated protein kinase-dependent Raf-1 activation.

Abstract

Our previous studies showed that berberine (BBR) increases liver low-density lipoprotein (LDL) receptor expression in an extracellular signal-regulated kinase (ERK)-dependent manner. This study was designed to explore the upstream cellular signaling molecules recruited by BBR to activate the ERK mitogen-activated protein kinase (MAPK) cascade. Chemical… (More)

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@article{Li2014BerberineUH, title={Berberine up-regulates hepatic low-density lipoprotein receptor through Ras-independent but AMP-activated protein kinase-dependent Raf-1 activation.}, author={Zheng Li and Jiandong Jiang and Weijia Kong}, journal={Biological & pharmaceutical bulletin}, year={2014}, volume={37 11}, pages={1766-75} }