Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials.

@article{Derosa2012BerberineOM,
  title={Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials.},
  author={Giuseppe Derosa and Pamela Maffioli and Arrigo Francesco Giuseppe Cicero},
  journal={Expert opinion on biological therapy},
  year={2012},
  volume={12 8},
  pages={
          1113-24
        }
}
INTRODUCTION Type 2 diabetes mellitus and hypercholesterolemia have proven to give an increased incidence of cardiovascular diseases (CVD). Recent studies have suggested that the natural alkaloid berberine could have pharmacological activities potentially useful in diabetes and hypercholesterolemia management. AREAS COVERED The aim of this review is to evaluate the metabolic properties of the natural alkaloid berberine, and its potential application to the treatment of diabetes and CVD… CONTINUE READING
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