Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model.

  title={Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model.},
  author={Yongguo Zhang and X. Wang and S. Sha and Shuli Liang and L. Zhao and L. Liu and Na Chai and H. Wang and Kaichun Wu},
  volume={83 6},
  • Yongguo Zhang, X. Wang, +6 authors Kaichun Wu
  • Published 2012
  • Medicine
  • Fitoterapia
  • Berberine, a compound isolated from Chinese Goldthread Rhizome, has been widely used as a non-prescription drug to treat diarrhoea in China. Previous studies have demonstrated multiple pharmacological activities for berberine, including its significant role in antimicrobial activity. However, its effect on ion exchange and water transfer remains unclear. The present study aims to explore the effect of berberine on the expression of Na(+)/H(+) exchanger3 (NHE3) and aquaporin4 (AQP4) in both… CONTINUE READING
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