Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model.

@article{Zhang2012BerberineIT,
  title={Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model.},
  author={Yongguo Zhang and Xin Wang and Sumei Sha and Shuli Liang and Lina Zhao and Lin Liu and Na Il Chai and Honghong Wang and Kaichun Wu},
  journal={Fitoterapia},
  year={2012},
  volume={83 6},
  pages={
          1014-22
        }
}
Berberine, a compound isolated from Chinese Goldthread Rhizome, has been widely used as a non-prescription drug to treat diarrhoea in China. Previous studies have demonstrated multiple pharmacological activities for berberine, including its significant role in antimicrobial activity. However, its effect on ion exchange and water transfer remains unclear. The present study aims to explore the effect of berberine on the expression of Na(+)/H(+) exchanger3 (NHE3) and aquaporin4 (AQP4) in both… CONTINUE READING
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