Berberine improves endothelial function by reducing endothelial microparticles-mediated oxidative stress in humans.

@article{Cheng2013BerberineIE,
  title={Berberine improves endothelial function by reducing endothelial microparticles-mediated oxidative stress in humans.},
  author={Fei Xiong Cheng and Yan Wang and Jing Li and Chen Hao Su and Fang Wu and Wen-hao Xia and Zhen Yang and B Yu and Yan-Xia Qiu and Jun Tao},
  journal={International journal of cardiology},
  year={2013},
  volume={167 3},
  pages={936-42}
}
BACKGROUND Circulating endothelial microparticles (EMPs) lead to endothelial dysfunction by increasing oxidative stress. Berberine has a beneficial effect on endothelial function, but no data are available on the EMP-mediated oxidative stress. The present study tests the hypothesis that berberine contributes to the improvement of endothelial function in humans via inhibiting EMP-mediated oxidative stress in vascular endothelium. METHODS Twelve healthy subjects received a 1-month berberine… CONTINUE READING

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