Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells.

@article{Letaiov2006BerberineantiproliferativeAI,
  title={Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells.},
  author={Silvia Leta{\vs}iov{\'a} and Soňa Jantov{\'a} and L'ubos Cip{\'a}k and Marta M{\'u}{\vc}kov{\'a}},
  journal={Cancer letters},
  year={2006},
  volume={239 2},
  pages={
          254-62
        }
}
Berberine, an isoquinoline plant alkaloid, is widely distributed in plants used in the traditional Chinese medicine. It displays a wide range of biological activities and the mechanism of action. Our previous studies of the anticancer activity of berberine against the cancer cell lines HeLa and L1210 were extended to the human tumour U937 cell line and the murine melanoma B16 cell line growing in vitro. Cytotoxicity was measured by the growth inhibition assay and by the cell morphology… CONTINUE READING

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