Berberine: A naturally occurring phototoxic alkaloid

@article{Philogne1984BerberineAN,
  title={Berberine: A naturally occurring phototoxic alkaloid},
  author={Bernard J. R. Philog{\'e}ne and John T Arnason and G. H. Neil Towers and Z A Abramowski and Francisco Campos and Danielle Champagne and D L McLachlan},
  journal={Journal of Chemical Ecology},
  year={1984},
  volume={10},
  pages={115-123}
}
The isoquinoline alkaloid berberine, present in nine different plant families was found to be phototoxic to mosquito larvae. In the presence of near UV the LC50 for acute 24-hr toxicity was 8.8 ppm compared to 250 ppm for dark controls. Mosquito larvae that were treated with 10 ppm berberine plus near UV for 24 hr and then transferred to berberine-free water showed decreased larval survival and resulted in a smaller cumulative number of pupae and adults as compared to controls, during a… CONTINUE READING
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