Beraprost Is Mediated Through cAMP-Responsive Element in Vascular Endothelial Cells Transcriptional Stimulation of the eNOS Gene by the Stable Prostacyclin Analogue

Abstract

Beraprost sodium (BPS), an orally active prostacyclin analogue, has been reported to be beneficial in the treatment of primary pulmonary hypertension and obstructive peripheral arterial disease. Although BPS was originally described for its effects on platelet aggregation and vasodilatory response, the effect on endothelial cells has been poorly understood… (More)

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@inproceedings{Kurabayashi2003BeraprostIM, title={Beraprost Is Mediated Through cAMP-Responsive Element in Vascular Endothelial Cells Transcriptional Stimulation of the eNOS Gene by the Stable Prostacyclin Analogue}, author={Masahiko Kurabayashi and Kazuo Niwano and Masashi Arai and Koichi Tomaru and Tsuyoshi Uchiyama and Yoshio Ohyama}, year={2003} }