BerEp4, cytokeratin 14, and cytokeratin 17 immunohistochemical staining aid in differentiation of basaloid squamous cell carcinoma from basal cell carcinoma with squamous metaplasia.

@article{Linskey2013BerEp4C1,
  title={BerEp4, cytokeratin 14, and cytokeratin 17 immunohistochemical staining aid in differentiation of basaloid squamous cell carcinoma from basal cell carcinoma with squamous metaplasia.},
  author={Katy R Linskey and Devon C. Gimbel and Lawrence R. Zukerberg and Lyn McDivitt Duncan and Peter M Sadow and Rosalynn M Nazarian},
  journal={Archives of pathology & laboratory medicine},
  year={2013},
  volume={137 11},
  pages={
          1591-8
        }
}
CONTEXT Basaloid squamous cell carcinoma (bSCC) is an uncommon variant of squamous cell carcinoma, which may overlap histologically with basal cell carcinoma with squamous metaplasia (BCCm). OBJECTIVE To aid in the differentiation of these neoplasms using immunohistochemical staining because of the worse prognosis associated with bSCC. DESIGN Using immunohistochemical techniques, we investigated BerEp4, cytokeratin 17 (CK17), and cytokeratin 14 (CK14) protein expression in 25 cases of bSCC… CONTINUE READING
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