Ber-EP4-positive phenotype differentiates actinic keratosis from superficial basal cell carcinoma.

@article{Tope2000BerEP4positivePD,
  title={Ber-EP4-positive phenotype differentiates actinic keratosis from superficial basal cell carcinoma.},
  author={Whitney D. Tope and Mehran Nowfar-Rad and David A Kist},
  journal={Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]},
  year={2000},
  volume={26 5},
  pages={
          415-8
        }
}
BACKGROUND Well-defined histopathologic criteria exist to distinguish actinic keratosis (AK) from superficial basal cell carcinoma (BCC). A similar morphology of downwardly budding dysplastic keratinocytes may occur in both entities, creating potential for errors in diagnosis. A marker that could reliably distinguish these two lesions would overcome this difficulty in diagnosis. OBJECTIVE To investigate whether Ber-EP4 staining is useful in distinguishing AK from superficial BCC, and to… CONTINUE READING
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