Bep4 protein is involved in patterning along the animal-vegetal axis in the Paracentrotus lividus embryo.

@article{Romancino2001Bep4PI,
  title={Bep4 protein is involved in patterning along the animal-vegetal axis in the Paracentrotus lividus embryo.},
  author={Daniele P. Romancino and Giovanna Montana and Serena Dalmazio and Matthew Di Carlo},
  journal={Developmental biology},
  year={2001},
  volume={234 1},
  pages={107-19}
}
In sea urchin embryos, the initial animal-vegetal (AV) axis is specified during oogenesis but the mechanism is largely unknown. By using chemical reagents such as lithium, it is possible to shift the principal embryonic territories toward a vegetal fate. We have investigated the possibility of obtaining the same morphological effect as with lithium by utilizing Fabs against the maternal Bep4 protein that is localized in the animal part of Paracentrotus lividus egg and embryos. Incubation of… CONTINUE READING