Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts.

@article{Kermanshai2001BenzylII,
  title={Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts.},
  author={R Kermanshai and Brian E. McCarry and Jeffrey Rosenfeld and Peter S Summers and Elizabeth A. Weretilnyk and George J Sorger},
  journal={Phytochemistry},
  year={2001},
  volume={57 3},
  pages={427-35}
}
Papaya (Carica papaya) seeds were extracted in an aqueous buffer or in organic solvents, fractionated by chromatography on silica and aliquots tested for anthelmintic activity by viability assays using Caenorhabditis elegans. For all preparations and fractions tested, anthelmintic activity and benzyl isothiocyanate content correlated positively. Aqueous extracts prepared from heat-treated seeds had no anthelmintic activity or benzyl isothiocyanate content although both appeared when these… CONTINUE READING