Benzydamine hydrochloride buccal bioadhesive gels designed for oral ulcers: preparation, rheological, textural, mucoadhesive and release properties.

@article{Karavana2009BenzydamineHB,
  title={Benzydamine hydrochloride buccal bioadhesive gels designed for oral ulcers: preparation, rheological, textural, mucoadhesive and release properties.},
  author={Sinem Yaprak Karavana and Pelin G{\"u}neri and G{\"o}khan Ertan},
  journal={Pharmaceutical development and technology},
  year={2009},
  volume={14 6},
  pages={
          623-31
        }
}
This study developed and examined the characterization of Benzidamine hydrochloride (BNZ) bioadhesive gels as platforms for oral ulcer treatments. Bioadhesive gels were prepared with four different hydroxypropylmethylcellulose (HPMC) types (E5, E15, E50 and K100M) with different ratios. Each formulation was characterized in terms of drug release, rheological, mechanical properties and adhesion to a buccal bovine mucosa. Drug release was significantly decreased as the concentration and… CONTINUE READING
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