Benzodiazepines Counteract Rostral Anterior Cingulate Cortex Activation Induced by Cholecystokinin-Tetrapeptide in Humans
@article{Leicht2013BenzodiazepinesCR, title={Benzodiazepines Counteract Rostral Anterior Cingulate Cortex Activation Induced by Cholecystokinin-Tetrapeptide in Humans}, author={Gregor Leicht and Christoph Mulert and Daniela Eser and Philipp Gero S{\"a}mann and Matthias Ertl and Anna Laenger and Susanne Karch and Oliver Pogarell and Thomas Meindl and Michael Czisch and Rainer Rupprecht}, journal={Biological Psychiatry}, year={2013}, volume={73}, pages={337-344} }
17 Citations
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It is evident from many preclinical studies that neurosteroids modulate anxiety-related behavior but nevertheless many issues are far from being understood and a major issue of future research should be the elucidation of the mechanisms of action of neurosteroid both at the molecular, cellular and brain network level.
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- Psychology, BiologyThe world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
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Although at present, none of the putative biomarkers for anxiety disorders, obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) is sufficient and specific as a diagnostic tool, an abundance of high quality research has accumulated that should improve understanding of the neurobiological causes of anxiety disorders.
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- 2022
Using a recently developed computational model to disentangle conflict adaptation and response inhibition, the results suggest that conflict adaptation is mediated by GABA-A neurotransmission.
Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders.
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