Benzodiazepines Counteract Rostral Anterior Cingulate Cortex Activation Induced by Cholecystokinin-Tetrapeptide in Humans

G. Leicht; C. Mulert; D. Eser; P. Sämann; R. Rupprecht

DOI:10.1016/j.biopsych.2012.09.004

Corpus ID: 23586549

Benzodiazepines Counteract Rostral Anterior Cingulate Cortex Activation Induced by Cholecystokinin-Tetrapeptide in Humans

@article{Leicht2013BenzodiazepinesCR,
  title={Benzodiazepines Counteract Rostral Anterior Cingulate Cortex Activation Induced by Cholecystokinin-Tetrapeptide in Humans},
  author={G. Leicht and C. Mulert and D. Eser and P. S{\"a}mann and R. Rupprecht},
  journal={Biological Psychiatry},
  year={2013},
  volume={73},
  pages={337-344}
}

G. Leicht, C. Mulert, +2 authors R. Rupprecht
Published 2013
Psychology, Medicine
Biological Psychiatry

BACKGROUND Benzodiazepines modulate γ-aminobutyric acid type A (GABA(A)) receptors throughout the brain. However, it is not fully understood which brain regions within anxiety-related brain circuits are really responsible for their anxiolytic effects and how these regions interact. METHODS We investigated whether the benzodiazepine alprazolam affects activity in distinct brain regions within anxiety-related circuits during an experimental anxiety paradigm by means of functional magnetic… Expand

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