Benzodiazepine self-administration in humans and laboratory animals – implications for problems of long-term use and abuse

@article{Griffiths1997BenzodiazepineSI,
  title={Benzodiazepine self-administration in humans and laboratory animals – implications for problems of long-term use and abuse},
  author={Roland R. Griffiths and Elise M. Weerts},
  journal={Psychopharmacology},
  year={1997},
  volume={134},
  pages={1-37}
}
Abstract Drug reinforcement may represent the primary behavioral-pharmacological mechanism underlying two types of problematic use of benzodiazepines – recreational abuse by polydrug abusers and inappropriate chronic use by patients. High dose polydrug abuse for the purpose of getting high is readily recognized as a significant social problem. Inappropriate chronic benzodiazepine use is more subtle but relatively common: for anxiolytics, 36% of past-year users (3% of the adult population in the… 

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