Benzodiazepine receptors in the post-mortem brain of suicide victims and schizophrenic subjects

@article{Pandey1997BenzodiazepineRI,
  title={Benzodiazepine receptors in the post-mortem brain of suicide victims and schizophrenic subjects},
  author={Ghanshyama N. Pandey and Robert R. Conley and Subhash C Pandey and Sudhir Goel and John E. Smialek},
  journal={Psychiatry Research},
  year={1997},
  volume={71},
  pages={137-149}
}
To examine the role of benzodiazepine (BZ) receptors in suicide and schizophrenia, we determined BZ receptors in post-mortem brain (Brodmann's area 10) obtained from suicide victims, schizophrenic patients, and control subjects using [3H]RO15-1788 as the radioligand. The maximum number of binding sites (Bmax) of BZ receptors in the cortex of suicide victims was significantly higher compared with controls, but this increase was mainly due to those suicide victims who died by violent means and… CONTINUE READING
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