Benzodiazepine receptor ligand actions on GABA responses. Benzodiazepines, CL 218872, zopiclone.

Abstract

The effects on GABA (4-aminobutyric acid) responses of several benzodiazepine and nonbenzodiazepine benzodiazepine receptor ligands were examined using mouse spinal cord neurons in dissociated cell culture. Diazepam, clonazepam and nitrazepam enhanced GABA responses potently at low nanomolar concentrations. Diazepam and clonazepam were most potent with… (More)

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Cite this paper

@article{Skerritt1984BenzodiazepineRL, title={Benzodiazepine receptor ligand actions on GABA responses. Benzodiazepines, CL 218872, zopiclone.}, author={J H Skerritt and Robert L Macdonald}, journal={European journal of pharmacology}, year={1984}, volume={101 1-2}, pages={127-34} }