Benzodiazepine receptor autoradiography in corpus striatum of rat after large frontal cortex lesions and chronic treatment with diazepam.

@article{Moratalla1989BenzodiazepineRA,
  title={Benzodiazepine receptor autoradiography in corpus striatum of rat after large frontal cortex lesions and chronic treatment with diazepam.},
  author={R Moratalla and Timothy M. Barth and Norman G. Bowery},
  journal={Neuropharmacology},
  year={1989},
  volume={28 9},
  pages={893-900}
}
It has previously been shown that diazepam impairs behavioural recovery from partial unilateral ablation of the cerebral cortex in rats. The present study confirmed this in rats with large unilateral lesions of the frontal cortex and showed that diazepam (5 mg/kg i.p. daily for 14 days immediately after surgery) prevented recovery from sensory asymmetry… CONTINUE READING