Benzodiazepine metabolism in ethanol-treated male rats: use of pair-fed and age-matched controls.

@article{Mason1992BenzodiazepineMI,
  title={Benzodiazepine metabolism in ethanol-treated male rats: use of pair-fed and age-matched controls.},
  author={Sir Ronald Mason and Paul E B Reilly and Lynley C Ward},
  journal={Alcohol and alcoholism},
  year={1992},
  volume={27 2},
  pages={143-52}
}
The effects of chronic moderate (15%) ethanol consumption and ageing on rat hepatic cytochrome P450 monooxygenase activities were examined using diazepam, nordazepam, d-benzphetamine, erythromycin, ethylmorphine and nitrosodimethylamine (NDMA) as substrates. In addition, the effects of moderate ethanol alone on the oxidation of metoprolol, morphine and… CONTINUE READING