Benzodiazepine-Associated Carcinogenesis: Focus on Lorazepam-Associated Cancer Biomarker Changes in Overweight Individuals

@article{Ku2018BenzodiazepineAssociatedCF,
  title={Benzodiazepine-Associated Carcinogenesis: Focus on Lorazepam-Associated Cancer Biomarker Changes in Overweight Individuals},
  author={Shih-Chieh Ku and Pei-Shen Ho and Y. Tseng and T. Yeh and Shu-Li Cheng and Chih-Sung Liang},
  journal={Psychiatry Investigation},
  year={2018},
  volume={15},
  pages={900 - 906}
}
  • Shih-Chieh Ku, Pei-Shen Ho, +3 authors Chih-Sung Liang
  • Published 2018
  • Psychology, Medicine
  • Psychiatry Investigation
  • Objective Cellular, animal, and human epidemiological studies suggested that benzodiazepines increase the risk of cancer and cancer mortality. Obesity is also clearly linked to carcinogenesis. However, no human studies have examined benzodiazepine-associated carcinogenesis as assessed by changes in cancer biomarkers. Methods A total of 19 patients were recruited, and received a 6-week treatment of 0.5 mg lorazepam. The measured cancer biomarkers were angiopoietin-2 (ANG-2), soluble CD40 ligand… CONTINUE READING
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