Benzimidazole analogs inhibit respiratory syncytial virus G protein function.

  title={Benzimidazole analogs inhibit respiratory syncytial virus G protein function.},
  author={Carrie W. Evans and Colm Atkins and Ashish K Pathak and Brian E. Gilbert and James W. Noah},
  journal={Antiviral research},
Human respiratory syncytial virus (hRSV) is a highly contagious Paramyxovirus that infects most children by age two, generating an estimated 75,000-125,000 hospitalizations in the U.S. annually. hRSV is the most common cause of bronchiolitis and pneumonia among infants and children under 1year of age, with significant mortality among high-risk groups. A regulatory agency-approved vaccine is not available, and existing prophylaxis and therapies are limited to use in high-risk pediatric patients… CONTINUE READING
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