Benzedrine and dexedrine in the treatment of children's behavior disorders.

  title={Benzedrine and dexedrine in the treatment of children's behavior disorders.},
  author={Charles Bradley},
  volume={5 1},
  • C. Bradley
  • Published 1 January 1950
  • Psychology, Medicine
  • Pediatrics
The effect of benzedrine® (dl-amphetamine) and dexedrine® (d-amphetamine) sulfates upon the behavior of maladjusted children was studied in the somewhat controlled setting of a children's psychiatric hospital. Twelve years' experience with these drugs is reported involving observations upon 275 children who received benzedrine®, 113 who received dexedrine® and 82 who received both preparations. The most frequent optimal daily dose was 20 mg. of benzedrine® and 10 mg. of dexedrine®. Specific… 
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THE USE OF amphetamine for the therapy of behavior disorders and learning disorders in children is a well-established clinical tradition. 1-3 As early as 1937 Molitch and Eccles 4 published a
Do typical clinical doses of methylphenidate cause tics in children treated for attention-deficit hyperactivity disorder?
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  • 1999
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There is a similarity in the pharmacologic properties, side effects, and abuse liability of dextro-amphetamine, methamphetamine, methylphenidate, and phenmetrazine.
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    Expert opinion on investigational drugs
  • 2001
This formulation represents a valuable addition to the available pharmacotherapeutic options for ADHD by providing an amphetamine-based stimulant offering the advantages of once-daily dosing accompanied by the clinical benefits of ADHD symptom control associated with the now widely used Adderall preparation.
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Methylphenidate appears to be a safe and effective treatment for attention-deficit hyperactivity disorder in the majority of children with comorbid tic disorder.