Benign hereditary chorea.

  title={Benign hereditary chorea.},
  author={Galit Kleiner-Fisman},
  journal={Handbook of clinical neurology},
Benign hereditary chorea (BHC) is a hyperkinetic movement disorder that historically has been characterized as a nonprogressive, dominantly inherited, childhood-onset chorea with normal intelligence. However, in some cases, atypical features were described such that controversy arose regarding whether BHC was a single syndrome. In 2002, a candidate gene, thyroid transcription factor (TITF-1), was identified to cause at least some cases of BHC. Since that time, the classical phenotype has… CONTINUE READING