Benidipine reduces ischemia reperfusion-induced systemic oxidative stress through suppression of aldosterone production in mice

Abstract

Aldosterone is implicated in the pathogenesis of several cardiovascular diseases, including ischemia reperfusion (I/R) and myocardial infarction, and also causes oxidative stress and inflammation in cardiovascular systems. Benidipine, a long-acting T- and L-type calcium channel blocker, reduces infarct size following myocardial I/R in rabbits. Benidipine… (More)
DOI: 10.1038/hr.2011.183

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Cite this paper

@article{Ohtani2012BenidipineRI, title={Benidipine reduces ischemia reperfusion-induced systemic oxidative stress through suppression of aldosterone production in mice}, author={Keisuke Ohtani and Soichiro Usui and Shuichi Kaneko and Shin-ichiro Takashima and Katsunori Kitano and Kanako Yamamoto and Masaki Okajima and Hiroshi Furusho and Masayuki Takamura}, journal={Hypertension Research}, year={2012}, volume={35}, pages={287-294} }