Benfluorex and Unexplained Valvular Heart Disease: A Case-Control Study

Abstract

BACKGROUND Recent case reports suggest that benfluorex, a fenfluramine derivative used in the management of overweight diabetic patients and dyslipidemia, is associated with cardiac valve regurgitation. METHODS We conducted a case-control study. Eligible patients were those admitted in the cardiology or the cardiac surgery units of our hospital between… (More)
DOI: 10.1371/journal.pone.0010128

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