Benefits of methylated cyclodextrins in the development of midazolam pharmaceutical formulations.

Abstract

Midazolam (MDZ) is a benzodiazepine commonly administered in preanesthesia of children by oral or by sublingual routes. To mask its bitter taste and enhance its aqueous solubility, we already developed a 0.2% (w/v) MDZ oral solution containing γ-cyclodextrin (γ-CD), which proves to be better accepted by children in pediatrics at University Hospital of… (More)
DOI: 10.1002/jps.23558

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Cite this paper

@article{Mathiron2013BenefitsOM, title={Benefits of methylated cyclodextrins in the development of midazolam pharmaceutical formulations.}, author={David Mathiron and Fr{\'e}d{\'e}ric Marçon and Jean-Marc Dubaele and Dominique Cailleu and Serge Pilard and Florence Djeda{\"{i}ni-Pilard}, journal={Journal of pharmaceutical sciences}, year={2013}, volume={102 7}, pages={2102-11} }