Benefits of colonoscopic surveillance and prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer mutations.

@article{Syngal1998BenefitsOC,
  title={Benefits of colonoscopic surveillance and prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer mutations.},
  author={Sapna Syngal and Jane C. Weeks and Deborah Schrag and Judy E Garber and Karen M. Kuntz},
  journal={Annals of internal medicine},
  year={1998},
  volume={129 10},
  pages={787-96}
}
Colorectal cancer is the second leading cause of cancer-related death in the United States [1]. Up to 15% of patients with colorectal cancer have a first-degree relative with the disease [2, 3]. In most cases, risk for colorectal cancer is likely to be a complex interaction of genetic and environmental factors. In a subset of patients, however, increased susceptibility to colorectal cancer is inherited through a single gene mutation. Genetic testing for predisposition to cancer is now possible… CONTINUE READING

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