Benefits of Atrial Substrate Modification Guided by Electrogram Similarity and Phase Mapping Techniques to Eliminate Rotors and Focal Sources Versus Conventional Defragmentation in Persistent Atrial Fibrillation.

OBJECTIVES This prospective study compared the efficacy of atrial substrate modification guided by a nonlinear phase mapping technique with that of conventional substrate ablation. BACKGROUND The optimal ablation strategy for persistent atrial fibrillation (AF) was unknown. METHODS In phase 1 study, we applied a cellular automation technique to simulate… CONTINUE READING