Benefits and risks of interferon therapy for hepatitis B.

  title={Benefits and risks of interferon therapy for hepatitis B.},
  author={Robert P. Perrillo},
  volume={49 5 Suppl},
UNLABELLED Alpha interferon is the only licensed drug for hepatitis B with immunomodulatory as well as viral inhibitory properties. Potential advantages of interferon compared to nucleoside analogs include a lack of drug resistance, a finite and defined treatment course, and a higher likelihood for hepatitis B surface antigen (HBsAg) clearance. Approximately 30% of hepatitis B e antigen (HBeAg)-positive and 40% of HBeAg-negative cases have a sustained virological response (when defined as HBeAg… CONTINUE READING


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