Benefits and Harms of Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia

@article{Shekelle2018BenefitsAH,
  title={Benefits and Harms of Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia},
  author={P. Shekelle and Ian Cook and I. Miake-Lye and Marika Booth and Jessica M. Beroes and S. Mak},
  journal={Annals of Internal Medicine},
  year={2018},
  volume={168},
  pages={414-421}
}
Cranial electrical stimulation (CES) is a noninvasive method of applying low-intensity electrical current to the head. It is related to but distinct from other forms of transcranial electrical stimulation, including electroconvulsive therapy and transcranial direct current stimulation. Versions of transcranial electrical stimulation vary in the placement of electrodes and the intensity and waveform of the current (1). According to Guleyupoglu and colleagues (1), CES evolved from the concept of… Expand
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TLDR
This chapter gives an overview of CES history, of evidence for CES efficacy for diverse clinical conditions, discusses proposed mechanisms of action, safety and regulatory issues, and the future of CES. Expand
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There are insufficient methodologically rigorous studies of cranial electrical stimulation in treatment of acute depression, and there is a need for double-blind randomized controlled trials of CES in the treatment of severe depression. Expand
Effects of cranial electrotherapy stimulation on resting state brain activity
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Results suggest that CES causes cortical brain deactivation, with a similar pattern for high‐ and low‐frequency stimulation, and alters connectivity in the default mode network (DMN). Expand
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It is suggested that CES may reduce symptoms of anxiety in GAD, and the use of CES in clinical settings should be explored. Expand
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Evaluating the efficacy of non-invasive cortical stimulation techniques in the treatment of chronic pain found a small effect with heterogeneity, but no difference between low-frequency stimulation and rTMS applied to the prefrontal cortex compared to sham for reducing pain intensity at short-term follow-up was found. Expand
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  • Medicine
  • Archives of otolaryngology--head & neck surgery
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To the Editor .—I was pleased to read that Dr Dobie has explored electrical tinnitus suppression, as reported in the July 1986 issue of theArchives, 1 but his success rate was extremely poor andExpand
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